Bottle of Lies: The Inside Story of the Generic Drug Boom

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Katherine Eban
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Ecco 2019-5-14 Hardcover 9780062338785

具体描述

Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.

Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?

Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.

The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?

A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

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##「仿制药的真相」: - 仿制药(generic drug),在英文中是与brand-name drug对立的。90年代开始对大药厂的仇恨情绪被转化为了对generic drug的喜好。 - Generic drug工厂主要在印度和中国;两国内的generic drug行业有一个共同目标:为吃不上药的人提供便宜的好药(例如西普拉...  

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##这本书像一个加长版bad blood 都是从上到下做假 不在意生产过程 该work的行业标杆FDA水土不服监管失灵 whistle blower心惊胆战地揭秘但是调查迟缓 可以感受到对global south的凝视 印象最深刻的是对whistle blower的比喻:大家都听说过可是没有人见过他们 说起仿制药的话题,相信绝大多数朋友第一时间想到的都是那部现象级的电影《我不是药神》的描写:效果和正牌药一模一样,往往都在印度那边生产,因为相关法律问题国内很难弄到…… 不过我对仿制药的印象却和那部电影不太一样,因为我的亲叔叔就患有慢粒细胞白血病,需要服用影片...  

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##「仿制药的真相」: - 仿制药(generic drug),在英文中是与brand-name drug对立的。90年代开始对大药厂的仇恨情绪被转化为了对generic drug的喜好。 - Generic drug工厂主要在印度和中国;两国内的generic drug行业有一个共同目标:为吃不上药的人提供便宜的好药(例如西普拉...  

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##「仿制药的真相」: - 仿制药(generic drug),在英文中是与brand-name drug对立的。90年代开始对大药厂的仇恨情绪被转化为了对generic drug的喜好。 - Generic drug工厂主要在印度和中国;两国内的generic drug行业有一个共同目标:为吃不上药的人提供便宜的好药(例如西普拉...  

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